Optimising clinical trial methods for complex regional pain syndrome: a methodological framework (OptiMeth-CRPS)

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ERDERA publication

Complex regional pain syndrome (CRPS) is a rare, disabling pain disorder. Systematic reviews have identified a critical lack of high-quality clinical trial evidence to inform the management of CRPS. There is an urgent need to find solutions to the methodological challenges of undertaking clinical trials in CRPS. The aim of this project was to develop a methodological framework for optimising future clinical trials in CRPS (OptiMeth-CRPS).
technology-3519754_1280

Year of publication

2025

Author

Keith M. Smart a,b,c, *, Victoria Abbott-Fleming d , Frank Birklein e , Stephen Bruehl f , Erica Corcoran g , Simon Day h , Michael C. Ferraro i,j , Sharon Grieve k,l , Ralf-Dieter Hilgers m , Carolyn Ingram a , David J. Keene n , Franz K¨onig o , Candida McCabe l , Stavros Nikolakopoulos p,q , Neil E. O’Connell r

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